DPCstruct | MC335

Metacluster Properties and Pfam Annotations

Number of structural domains39
Mean domain length (aa)139 ± 27 aa
Standard deviation of domain lengths26.55
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score87.46
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)32.07
Pfam Score100.00
Assigned Pfam label(s) PF00909

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A060W899 63-186 AVGTAAEFMLMPYGSLIIGFCCGIISTLGYIYITPFMEKYLKIQDTCGIHNLHAMPGVIGGIVGAVTAAAASEGVYGKAGLINTFDF…
A0A3P7ZZM5 10-164 VLYPSHAVAVGICASFVSVIGHAWLSPKLEKRFKLYDTCGVHNLHGIPGILAGIFSIIFALGYEPESYGKTLYHIYPYFEGGPMEGD…
A0A444TJH6 4-150 None
A0A7R8H903 22-116 None
A0A6L5CQY4 117-323 None
A0A834ACJ7 37-168 None
A0A1A9XXG3 1-128 None
T1DNL1 24-187 None
A0A813SEJ2 347-463 None
A0A6G0S7N2 148-284 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.