DPCstruct | MC33446

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)149 ± 14 aa
Standard deviation of domain lengths14.05
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score89.98
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)27.55
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3D5M055 3-138 RRSGRKAYYAGDYQTCYQNFFGKELDETEQVMYSKSESILTIRMWLREYEVFVNEGSELEALDSLLQAVHDYPSLLNYATEYNAQDE…
R7QTS3 28-168 GYSVFKGEAQDSYKQGDYVTAYAKLEGAKIKSADEDFYNRTALLAAIQEEYDSYQSMMQIGKTEMALDCLIRGVGRCDNHAEKAEEY…
A0A3A9EZB5 18-156 None
A0A1H7HG11 922-1080 None
A0A3A9D4A3 402-555 None
D4J323 5-147 None
A0A0K8J6V2 398-537 None
R5WCS7 297-434 None
A0A1D9P1F6 619-768 None
A0A1G6AQV6 426-593 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.