DPCstruct | MC33438

Metacluster Properties and Pfam Annotations

Number of structural domains34
Mean domain length (aa)467 ± 116 aa
Standard deviation of domain lengths115.68
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score90.70
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)48.58
Pfam Score96.67
Assigned Pfam label(s) CL0023- CL0603- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A402FFY9 1-507 TPTPLGEGKSTVTIGLVQALTAHLKVNSFACLRQPSQGPTFGVKGGAAGGGYAQVIPMEEFNLHLTGDIHAITAANNLLAAAIDARI…
A0A2X1WLX8 1-252 MNDRSLRNVVISLGKKADGFPREDHFMITVASEIMAVLCLAESIEDLKNRIAKMVIGYNLDGNPVTVADLEIQGAVAMLLKDALKPN…
A0A059D652 25-545 None
A0A665W8F4 195-790 None
A0A812LKM4 23-324 None
A0A553MV03 336-900 None
A0A6G0XHM6 79-627 None
A0A5A9NF52 664-1255 None
A0A498MXD7 166-667 None
M7C472 54-694 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.