DPCstruct | MC3343

Metacluster Properties and Pfam Annotations

Number of structural domains154
Mean domain length (aa)144 ± 25 aa
Standard deviation of domain lengths24.56
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score72.95
Mean fraction of residues predicted as intrinsically disordered0.49
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)18.78
Pfam Score100.00
Assigned Pfam label(s) PF18821

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1J5P8V5 4-129 ATAGAKKAFALEDARIQVDRRHQRIEYHDLTGRVRMTDSGPRVDVHIADTDTIEAGLRLSAQKFGGEVFITGEAAFREQSARQAARL…
A0A0F0DMZ7 35-164 RRLTIRSARPVQPNAILYDGPVITHRVQRNGDVEYQRNGAALLVDQGKSVRLWQNDRDAIEIALRLAQRKFGPVLELTGPLEFQMEA…
A0A1E9JVJ6 554-714 None
A0A2K4W4E8 1-113 None
A0A1B8Q4H9 98-319 None
A0A3S4DY75 46-172 None
A0A7D5YUX3 232-403 None
B7UEZ2 694-826 None
A0A2N0DU62 56-168 None
Y0KHP2 448-619 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.