DPCstruct | MC33403

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)495 ± 116 aa
Standard deviation of domain lengths115.86
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score78.48
Mean fraction of residues predicted as intrinsically disordered0.42
Mean length-normalized TM-Score0.27
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)20.09
Pfam Score81.55
Assigned Pfam label(s) CL0067- PF05622- CL0188

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R8ZB44 87-601 SRPRFRPMFISQNFGSCLENPNKLTDYEDLADGVLVYEVLLQIDPEPAHHGVLPSFGNALVRTRNMDIVIKNMKALYEEELCQVLLV…
A0A1B0DCV9 16-327 TSLLDGAIINSVVLQIDPEPQHHLVKLIGLDGVLLANARARNFDAIVRNLRNLYEEELCQRVLILPDCSVLGHSPETPQGLEQMKLL…
A0A7M4F9L2 2-461 None
A0A1Y1VDE2 9-467 None
A0A1B0A799 8-451 None
A0A6S7GDF3 35-589 None
F4Q6U0 5-660 None
A0A1B0BZT3 117-651 None
B6AGJ8 1-579 None
T1FWU2 18-413 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.