DPCstruct | MC33385

Metacluster Properties and Pfam Annotations

Number of structural domains467
Mean domain length (aa)154 ± 26 aa
Standard deviation of domain lengths25.86
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score80.25
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)19.35
Pfam Score97.23
Assigned Pfam label(s) PF14774- CL0673- CL0127- PF04757- PF06271

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2N5XJP1 3-139 RPAGSGWRLLARVVDSLLVGFVGSLVLWTVLGFPDYGSAPGLLYSGLVALLYLVYEGVMLSRDGQTVGKKLVRIRVAMLADGSSPPA…
A0A2N2P197 5-175 YAGLWTRILAFGFDYLPIAIYLGVVVMLGLALGAAFPELQQVVFGNPVSGQIAGFFIVTVPISLYFVLFESSAWQATWGKRKRHLQV…
A0A221R1R0 18-172 None
A0A401FIK8 2-132 None
A0A3D2C8C4 4-127 None
A0A7V3ADE4 382-537 None
A0A1W1XV48 90-231 None
A0A519MXZ7 154-298 None
A0A356FXV1 5-147 None
A0A0G1FLC7 94-247 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.