DPCstruct | MC33363

Metacluster Properties and Pfam Annotations

Number of structural domains70
Mean domain length (aa)165 ± 25 aa
Standard deviation of domain lengths25.17
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score88.72
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)36.15
Pfam Score100.00
Assigned Pfam label(s) CL0137

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A174KCX2 8-120 QKEHAAAFTHGGKFHADDVFSAALLLHFNPQLTIQRGNRVPEDFAGIVFDIGRGEYDHHQKDSRIRENQVPYAAFGLLWEALGTEIL…
A0A6J1PWS5 5-176 DPALPTMSIVRIGTKDGPFHCAEVLACALLKLLPQYKNASIVRSQDRSVLDNCDIVVGVGGEYDSPRHRYDHHVREFQESVSTIIKK…
A0A7R8XAJ6 142-330 None
A0A415ZKH7 4-156 None
A0A3R6IGP7 45-167 None
A0A7U6KKD0 12-157 None
K8F387 65-223 None
A0A812ZQZ0 2-173 None
A0A4V4MDN2 365-557 None
A0A654GVN0 2-175 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.