DPCstruct | MC33305

Metacluster Properties and Pfam Annotations

Number of structural domains59
Mean domain length (aa)154 ± 21 aa
Standard deviation of domain lengths20.56
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score90.33
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)35.39
Pfam Score100.00
Assigned Pfam label(s) PF02595

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A366JQY8 18-173 GHLIYVDATGPVGKKVNAHFGIFAENGEKTAVIEMAAVAGLKHVPLQERNPLLTTTYGVGELILAALDFGADRILIGCGDSGTSDGG…
A0A378F2T3 1-118 MWQQQRCTSPYGLSLQADFLILPGERAIIEMAQSCGLELTPPAQRDVRQASSYGLGEQVKAALDAGCRHLIIGLGGSATNDGGIGFA…
A0A2P1G4L8 55-231 None
A0A2T2XAB7 58-188 None
A0A2W5SXE2 134-292 None
A0A447N6H1 375-556 None
A0A6N6X5M5 1-130 None
A0A0F9IS93 62-231 None
A0A522QWC4 22-171 None
A0A512DEA5 36-186 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.