DPCstruct | MC33271

Metacluster Properties and Pfam Annotations

Number of structural domains5041
Mean domain length (aa)232 ± 52 aa
Standard deviation of domain lengths51.66
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score71.03
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.33
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)13.05
Pfam Score72.57
Assigned Pfam label(s) CL0221- PF01412- PF14008- PF18701- CL0110

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183AWU3 2-154 None
A0A2J6PLX2 204-445 None
A0A1I7S5C4 11-251 None
A0A183BAH8 50-226 None
A0A6J1PKR3 166-460 None
A0A5N6NCF9 26-320 None
A0A5N6NDY0 25-228 None
A0A4Y2ASQ8 1-213 None
A0A4Y2AKG1 82-280 None
A0A4Y2AJJ1 98-379 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.