DPCstruct | MC33271

Metacluster Properties and Pfam Annotations

Number of structural domains5041
Mean domain length (aa)232 ± 52 aa
Standard deviation of domain lengths51.66
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score71.03
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.33
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)13.05
Pfam Score72.57
Assigned Pfam label(s) CL0221- PF01412- PF14008- PF18701- CL0110

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E4XJP0 126-410 None
W2ZIN7 74-274 None
A0A3L8Q8Z4 165-476 None
A0A0V0ZRY6 281-487 None
A0A0V0ZID6 121-284 None
A0A821UH16 451-680 None
A0A7J6FIG5 2-223 None
A0A3L6PMK6 2-182 None
A0A1U8N7N3 24-250 None
A0A1U8MWC4 117-384 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.