DPCstruct | MC33271

Metacluster Properties and Pfam Annotations

Number of structural domains5041
Mean domain length (aa)232 ± 52 aa
Standard deviation of domain lengths51.66
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score71.03
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.33
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)13.05
Pfam Score72.57
Assigned Pfam label(s) CL0221- PF01412- PF14008- PF18701- CL0110

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A817SF84 19-232 PIFSGHPSEDVELFLRSIKNITKANDESENHEILEIVRGKLTQSAGLWFDNNEHNFKKWSDFEIAFRNRYFSTTMIHKKFNKLKQRT…
A0A6P7VZY8 4-165 TPTYSGYSDAASVHDFLQDLDAYIAALGASDETALIQIVPIALTDDAARWRRMQRPFLSMADFRTRFREEFLPPDYEMRIRDELASR…
A0A0R3UFP8 17-225 None
A0A4V4HAU1 12-322 None
A0A4S8M835 143-447 None
J6F686 4-297 None
J6F537 8-267 None
A0A6I9Y9M0 848-1061 None
J5TDH1 4-181 None
A0A0G4HQC0 7-251 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.