DPCstruct | MC33247

Metacluster Properties and Pfam Annotations

Number of structural domains4760
Mean domain length (aa)134 ± 28 aa
Standard deviation of domain lengths28.39
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score85.08
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)13.41
Pfam Score93.32
Assigned Pfam label(s) CL0020- PF09673- CL0613- CL0080- CL0010

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A074L3B8 148-283 None
A0A4Q2U7W9 2-167 None
A0A0P7BS47 480-676 None
A0A3E0KNT0 25-169 None
A0A367KH57 982-1146 None
A0A367K6A4 1-90 None
A0A537WTU4 6-88 None
E3NE71 9-162 None
A0A3P8KEL2 283-394 None
A0A7Y3ESB4 14-171 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.