DPCstruct | MC33247

Metacluster Properties and Pfam Annotations

Number of structural domains4760
Mean domain length (aa)134 ± 28 aa
Standard deviation of domain lengths28.39
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score85.08
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)13.41
Pfam Score93.32
Assigned Pfam label(s) CL0020- PF09673- CL0613- CL0080- CL0010

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3B6FWK4 62-191 None
A0A3D6DD41 22-153 None
A0A0U2WMW5 3-93 None
A0A7T9PGP6 16-162 None
A0A1Y4BSR5 6-163 None
H3HAZ6 180-289 None
H3H6P0 144-270 None
A0A7W8T945 2-137 None
A0A7C5H3F5 61-176 None
A0A7C4PMY7 78-194 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.