DPCstruct | MC33247

Metacluster Properties and Pfam Annotations

Number of structural domains4760
Mean domain length (aa)134 ± 28 aa
Standard deviation of domain lengths28.39
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score85.08
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)13.41
Pfam Score93.32
Assigned Pfam label(s) CL0020- PF09673- CL0613- CL0080- CL0010

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
U3ILX7 313-422 None
A0A493TZG3 13-147 None
A0A840D323 111-226 None
A0A0S2ITZ5 28-199 None
A0A2V5RGH9 5-163 None
A0A2C6KH97 645-783 None
A0A1I8C3G4 2-183 None
A0A812X3Z0 972-1086 None
A0A812VT01 41-179 None
A0A812VGQ1 26-130 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.