DPCstruct | MC33247

Metacluster Properties and Pfam Annotations

Number of structural domains4760
Mean domain length (aa)134 ± 28 aa
Standard deviation of domain lengths28.39
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score85.08
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)13.41
Pfam Score93.32
Assigned Pfam label(s) CL0020- PF09673- CL0613- CL0080- CL0010

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6I4ZHF5 59-218 None
A0A6P0VJV3 3-146 None
A0A850LRG5 79-182 None
A0A7I0KG84 6-135 None
A0A2K3P3T5 2-115 None
A0A2K3P2Z4 581-687 None
A0A6L7LFG5 88-231 None
A0A2K3P0S6 663-771 None
A0A7X8W769 24-130 None
A0A521GU20 675-836 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.