DPCstruct | MC33247

Metacluster Properties and Pfam Annotations

Number of structural domains4760
Mean domain length (aa)134 ± 28 aa
Standard deviation of domain lengths28.39
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score85.08
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)13.41
Pfam Score93.32
Assigned Pfam label(s) CL0020- PF09673- CL0613- CL0080- CL0010

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4V2A849 9-134 FGDKVNSKTLKGKILVINFWFVGCAPCVQEIPELNKLVKDYERDSSIVFIAIALDKPWDIKDFLKKRPFYYKIIGDGRLTAKGYDVR…
A0A1B6NV80 11-140 YISSPSPYQDVVSAQQSAVKQDKLLLVVLGAQWCHDSTGLAERFSTKEMDLILRAHYETVFVDVGTLEDRRNITERFDYPIYYATPT…
A0A378NA57 2-90 None
A0A1P8W8V7 167-328 None
A0A7R9U210 200-311 None
A0A7W1HHH9 64-181 None
A0A4Y7NJ76 407-512 None
A0A6J7RF64 10-107 None
A0A353RWF6 18-173 None
A0A4Z0W0X1 227-386 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.