DPCstruct | MC33243

Metacluster Properties and Pfam Annotations

Number of structural domains72
Mean domain length (aa)375 ± 57 aa
Standard deviation of domain lengths56.88
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score85.53
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)20.99
Pfam Score65.12
Assigned Pfam label(s) CL0126- CL0159- PF07589- CL0202- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q6B6F5 1-384 MKNLYAFLSVFFFLSASVSAQVPKLNSYPSAAAVIYLDFDGHIIEGTSWNFEGPVVCNGANLNATQLTEIFNRVSEDYRPFNINVTT…
A0A6M0AUI7 4-284 DFSPFNVNVTTAQPSDDQLKKTSGSDSEWGIRVVIGGDGSWYNKPGVVGVGYLDSFNDDIDTPTFVFSEVYNGSEKGVAETISHEVG…
A0A517TTG6 16-348 None
A0A383W5S7 49-412 None
H5WUS2 3-312 None
A0A6M0G1P3 39-405 None
A0A6P1AE50 1-401 None
A0A7W0V802 2-268 None
A0A0D2MSH0 2-348 None
A0A3D3CRV0 2-237 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.