DPCstruct | MC33233

Metacluster Properties and Pfam Annotations

Number of structural domains35
Mean domain length (aa)93 ± 6 aa
Standard deviation of domain lengths6.40
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score94.22
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.95
Mean intra-cluster local Distance Difference Test score0.90
Mean intra-cluster sequence similarity (%)41.48
Pfam Score100.00
Assigned Pfam label(s) CL0143

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6V7VE81 1-89 MWIKVININGEITSFSWIENYDKLRNAVNITFPGFLVHEAVQWSDFYKKWFFLPRFASNVSPKDVKGENYGTNLLLIADENFTKIEA…
A0A2S2QJA0 13-106 VNNNPMWIKIINKFGHITHVNWVNNYIAIRKAANINFPGYMIHESCVWSQVHKRWFFLPRRSSSKQYNEDADEYMATNLLISASDNF…
D8M6R9 859-946 None
A0A0V0TZW1 942-1035 None
A0A0N4ZHE3 213-310 None
A0A3Q0ITQ8 74-162 None
A0A0S4JUI2 243-341 None
A0A7S1W5R3 308-402 None
A0A3P7EHT1 188-284 None
A0A498MTL7 444-530 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.