DPCstruct | MC33223

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)353 ± 21 aa
Standard deviation of domain lengths21.36
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score82.75
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)24.84
Pfam Score89.24
Assigned Pfam label(s) PF14666- CL0542- PF14664

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A512UIR2 1-363 MKDTSFKALVAGTKLLAIKDFDEWNWSLLSQLFQGPLRNPVRFIELQEKYPKFLKTFVSFLRPFKYRFSSVPIAASSKYPKIRKPKN…
A0A2R7WFG5 1-325 MLATWFLGPVLWGEAPLLCNLVDRSGLTEFMRHSDTLKKTTDSNKRLFVRRLVNFVLPVTGQYGRKEIGSDRKSSTKLTLAALSLFS…
B4I736 333-667 None
A0A7G2CLR6 227-574 None
A0A4Y9ZL48 587-916 None
U7Q2K3 677-1024 None
G0QUZ5 184-541 None
A0A4D5RVK5 90-435 None
Q4DDE7 599-966 None
A0A0D2GW13 680-1036 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.