DPCstruct | MC33206

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)80 ± 5 aa
Standard deviation of domain lengths5.05
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score82.23
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)54.36
Pfam Score100.00
Assigned Pfam label(s) CL0188

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2R7VX89 12-88 TMEALMESDLLRRAEIMLQQAGKLGCRSFVTPADVVNGVYKLNLAFVANLFNNHPGLEKPEGGIEGLENLEETREEK
A0A2A2JW08 188-268 IAPSGTGVSLAPLHVQGNVNRAGAMLDEAEKLDCREFVTPNDVATGNYKLNLAFVANLFNKHPNLPGPGADEIVEEVIQET
A0A4Z2HJM5 43-133 None
A0A3P6TUK5 17-93 None
A0A068Y5K4 164-251 None
A0A6I9NBS2 1-75 None
A0A2G8L3I6 1-82 None
A0A3P8I3I8 7-80 None
A0A0R3W065 7-83 None
A0A1X7VVY2 11-86 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.