DPCstruct | MC33118

Metacluster Properties and Pfam Annotations

Number of structural domains402
Mean domain length (aa)184 ± 46 aa
Standard deviation of domain lengths46.21
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score85.77
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)18.41
Pfam Score98.94
Assigned Pfam label(s) PF16455- PF11022- CL0670- CL0202

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2R7Q820 2-111 MGLDLEAWLEDEQACELWPGIVDHMEWARLQHCPLGPARGLTLVFSAKESLFKALYPTVGRYFDFLDARWLTMTEQTLTFELKSALT…
A0A1Q7GUW4 14-188 VEKDRRRFIAARAALRSIVGERIGVAPADVAFRYGSRGKPELEHASRAVRFNLSHSEDLCVIAVHDDREVGVDVERIRPLVDLDAVR…
A0A7T1HVU4 382-597 None
A0A6A6L4Y7 383-593 None
A0A6S8RXB0 122-341 None
A0A7G6ABD5 2-100 None
A0A7M3LQX0 39-233 None
A0A534KFA6 222-381 None
A0A2S7JF56 12-150 None
A0A7S2MRD3 6-196 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.