DPCstruct | MC33100

Metacluster Properties and Pfam Annotations

Number of structural domains95
Mean domain length (aa)164 ± 30 aa
Standard deviation of domain lengths30.45
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score80.10
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)20.93
Pfam Score78.52
Assigned Pfam label(s) CL0184- PF00772- CL0021- PF01281- PF03948

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7G2EQ94 860-1021 FNFEVVSQKKAKKLRKVILKEDVTDLGKQGQLLDVKAGFFRNFLLPTGKAQLMTPLLLKELKMEDERIEAEKQRVKEEAQQLAMVFQ…
A0A674BVH5 64-217 KVVEDTKHAPKEKMELILTQTVAKLGGRGDTVFVKKSVGRNNLLAQGLAVYPSPENKAMFAEELRTVEILKHMELKVEKRTSIEYDI…
A0A1E4SL08 3-230 None
A0A1D1YQT2 5-135 None
J5QBQ7 21-161 None
A0A7C7EY95 100-248 None
K7FIP8 39-197 None
A0A1W0XDW0 76-246 None
D3B775 26-184 None
A0A453Q4P8 1-123 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.