DPCstruct | MC33094

Metacluster Properties and Pfam Annotations

Number of structural domains43
Mean domain length (aa)125 ± 27 aa
Standard deviation of domain lengths27.31
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.20
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)34.02
Pfam Score100.00
Assigned Pfam label(s) CL0175

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y2APV9 14-121 NFRLDGPLGLRLDFEEEKKRVIAAAIEKVQFEMNEARRISEDQLKNAHLMEMATAVERHKTEISEVKKKQWCYNCEAEAIYHCCWNT…
A0A2H1C7A1 149-246 DSSLLKSLEERIHRIYADRLIALTTERDQACEEVSRQSALIAQLKRDHEAEVKRVKQRTWCQVCLNEAFYHCCLGTAYCSKTCQWQH…
A0A1I8F8N2 55-196 None
A0A5K4EVH0 764-914 None
A0A5K4F238 1094-1213 None
A0A834UXR1 281-402 None
A0A2D4ISH9 395-541 None
A0A0K0E905 28-175 None
A0A1S3P327 2-88 None
A0A7R9LWL5 6-99 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.