DPCstruct | MC33090

Metacluster Properties and Pfam Annotations

Number of structural domains52
Mean domain length (aa)98 ± 11 aa
Standard deviation of domain lengths10.62
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score83.84
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)16.00
Pfam Score66.67
Assigned Pfam label(s) CL0020- CL0354

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V3U165 7-94 ITSSHWSFGVEGRDPYTHVMRLHVNGEISGYQNTNEHRWAKDGDKILFFDAAGEVSSVFARNSDVVDAEHWSGVYNKNSQIRHQISRK
I4YML2 2-87 VGNWSVQTSGGSCRVQLSSSPALDLYRASASGCSNQDLSKVNAWDYRDGEVYLYQTGGSVTARLRGSSSSLSGVLAKSGAPLSLTR
A0A1I5KDB9 113-195 None
A0A837V1E0 2-87 None
A0A257VVR7 208-293 None
G8PMW9 47-147 None
G8PSJ6 2-98 None
A0A4Q9VW48 168-270 None
A0A1W9I0W4 126-227 None
A0A7G5LKD5 80-181 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.