DPCstruct | MC33054

Metacluster Properties and Pfam Annotations

Number of structural domains808
Mean domain length (aa)227 ± 36 aa
Standard deviation of domain lengths35.77
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score78.32
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.36
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)17.32
Pfam Score91.46
Assigned Pfam label(s) PF13884- PF04917- CL0606- CL0073- PF01391

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A812X5L2 12-225 None
A0A496KTV2 442-650 None
A0A1V0DHK4 18-250 None
A0A6P0K4S7 48-304 None
A0A1M3EDU9 149-378 None
A0A6A3RND3 365-591 None
A0A812ZC73 103-295 None
R6J0A2 590-844 None
A0A2E0AGK1 715-935 None
A0A439U4U9 313-539 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.