DPCstruct | MC33027

Metacluster Properties and Pfam Annotations

Number of structural domains149
Mean domain length (aa)109 ± 17 aa
Standard deviation of domain lengths16.74
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score81.10
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)34.29
Pfam Score95.53
Assigned Pfam label(s) PF16639- PF00238- CL0395- CL0021

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H0V064 4-117 TKTKLNVADNTGAKMVQCIGVPGGTRKRYAHLGQIIRVVVKVAAPRREVKKHQVLKAVIVRQHKPFRRADGSFLIFDDNACCLLNDN…
A0A5J9UVE5 17-125 SLGLPVAATVNCADNTGAKNLYIISVKGIKGRLNRLPSACVGDMVMATVKKGKPDLRKKVMPAVIVRQRKPWRRKDGVYMYFEDNAG…
A0A0E0M8I0 143-265 None
L0B028 176-281 None
A0A835J015 29-130 None
A0A814FLV2 13-126 None
A0A183MDH2 12-124 None
A0A7J6LDK7 3-102 None
A0A3M7HNS3 1-131 None
A0A6A2YDP7 115-220 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.