DPCstruct | MC33008

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)105 ± 7 aa
Standard deviation of domain lengths6.51
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score88.61
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.91
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)48.33
Pfam Score100.00
Assigned Pfam label(s) CL0715

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4W5KME0 1-123 MDINRLTHRLLSKHMTLDSFDAMFREANHNVSAPYGRITLHVFWELNFDFLPNYCYNGSTNRFVRTAIPFTQEPQRDKPANVQPYYL…
K7HKM5 1-106 MLIETNRLCHSLLSEVLHSIASFDDLLQEANHAVNSPHGRITLHVFWELMYDFVPNFVYNGSTHRFIRSRHVFRKTPAREKPPQVGQ…
A0A3P7YBM3 5-106 None
A0A183R869 175-274 None
A0A183KT23 2-107 None
A0A484MFB7 32-140 None
A0A6P7GPG7 314-415 None
A0A2H2ISS0 1-105 None
A0A183CN55 513-613 None
A0A0T6B7P9 196-298 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.