DPCstruct | MC32988

Metacluster Properties and Pfam Annotations

Number of structural domains82
Mean domain length (aa)140 ± 30 aa
Standard deviation of domain lengths29.54
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score83.92
Mean fraction of residues predicted as intrinsically disordered0.39
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)23.21
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A146I2X7 313-440 FIIWTPARALKRVQLVMDEFDKLKFSETLPLTFGAIPWPVLVDPVRMKVEDISWDAVEAFCRQAKLALLHDQAGYKSLVVSLHRMFH…
A0A4Y7TCF5 34-188 ERQRLNEQYQRDMAERRRAQASPSNRMNVDGPPAAPSIDDRLNDYEKRWDILTQKGARDLRFSDMPWPVLCDMRDLSALTPANIEPF…
A0A3M7HN66 199-399 None
A0A0C3BEJ5 102-205 None
A0A0C2ZW22 86-225 None
A0A146I2R5 502-626 None
A0A4S8MN21 3-117 None
K8ELK8 238-425 None
A0A061RBU3 171-306 None
A0A1J8QBC4 638-765 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.