DPCstruct | MC32978

Metacluster Properties and Pfam Annotations

Number of structural domains36
Mean domain length (aa)149 ± 24 aa
Standard deviation of domain lengths23.62
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score65.15
Mean fraction of residues predicted as intrinsically disordered0.76
Mean length-normalized TM-Score0.29
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)34.47
Pfam Score100.00
Assigned Pfam label(s) CL0511

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A182FPG2 15-121 LREFDREAKLAAAFPKGIQCQKCLEFGHWSYECKGKRKYLHRSSRTQLLKTNLKKLHNKQASEGNGNQAAPGTTDGVTKRSGKDKKK…
D0P073 7-169 EAPLGMWALRKEARRHMYETSTDQVRVHRRGLGSSSSSSVAAMCQKCLRRGHWTYECKNGAVYVQRPSRSQQLRNPKLRQPFNKEMP…
A0A445AWN1 50-183 None
A0A1Y1L451 3-111 None
A0A1S8W5U3 1-208 None
U6L3H5 1-164 None
A0A061R2M8 3-127 None
A0A1X0S793 5-133 None
A0A6P8ZTX3 1-136 None
I7MIN8 2-147 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.