DPCstruct | MC32936

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)141 ± 20 aa
Standard deviation of domain lengths19.78
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score80.84
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)22.56
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5C6SJX4 2-143 SSQRVTFDPANLPRPENMFERRGYIDQYIQYFHSDLAPQIAEKRESSYPVVCKFYHEKRGKIEVPSVYFEYVIDKTMWKNIFKPLGD…
A0A395MSS8 9-124 GPPPSPNFNPVDRETRKRFIKERFEHARQWNILQWEFFHKTAEYELCVKLHNADFEWVGAAFFDYLVDFASWAGYIEDRKLDHDQFC…
A0A366PK57 16-188 None
S0EEX4 4-131 None
X0AUX9 43-164 None
A0A1B8AJF4 9-142 None
A0A1L7VMA3 2-154 None
A0A420NCA8 1-136 None
A0A2H3GI29 4-148 None
A0A2K0WB64 5-138 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.