DPCstruct | MC32864

Metacluster Properties and Pfam Annotations

Number of structural domains104
Mean domain length (aa)182 ± 32 aa
Standard deviation of domain lengths31.79
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score87.16
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)17.83
Pfam Score78.43
Assigned Pfam label(s) PF07275- PF19854- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7X2NPM6 9-201 FPFAAFITNLGKYNEGELVGEWVKFPTTPEKLQEVFERIGIGSADDFGNPYEEWFITDYDCYVDGLYNLLGEYENLDELNYLASKLE…
A0A174X2Q3 3-192 LQATIKNGRHPEYGVVSIPFPIPKNEYDHVLELLKSLEIGDAVEQDCCVEKIRSDFFPILKRLETSYVNVDELDYLAKRLESFWDPE…
A0A655TCR8 21-214 None
A0A830WKS9 2-148 None
A0A4R1QP94 3-174 None
A0A1X7AMJ4 141-317 None
C7N820 3-201 None
A0A6I2QWQ8 141-304 None
A0A1C6J546 2-173 None
A0A7W4QY96 17-174 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.