DPCstruct | MC32740

Metacluster Properties and Pfam Annotations

Number of structural domains476
Mean domain length (aa)257 ± 60 aa
Standard deviation of domain lengths60.02
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score90.78
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)18.31
Pfam Score84.78
Assigned Pfam label(s) PF00557- CL0356- CL0260- CL0458- CL0544

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A177WSI2 11-248 ILKPDEIEKMRIVCKLGREILEEGKKAVKVGVTTDEIDRVIHEACMERDVYPSPLNYYNFPKSVCTSVNEVICHGIPDKYELQDGDI…
A0A7X5WC67 83-361 GGGRAARQRSGRGPAELADPGLILDDMRLVKEPAEIDAIRDAVRITIAAFRDALPLVRPGTGEWQVEAAVEAAFRDAGADGPAFATI…
A0A4Z1IW17 125-277 None
A0A7R9PTB6 105-277 None
C3ZF22 683-945 None
A0A1A9X9E0 412-645 None
S9SLB6 84-342 None
A0A2B4S140 18-261 None
A0A0K0EBT1 26-273 None
A0A1Q9T7N1 5-154 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.