DPCstruct | MC3273

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)136 ± 19 aa
Standard deviation of domain lengths19.08
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score81.61
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)21.62
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R5FW99 361-486 YIVNKEDLSTVCDNLYRVGIEGRSFHENSDIYNVFIREFYWSSIYSQAVVDEYYKKVPFSVGHKNFDNITIEPAYLQYALSSVADAS…
A0A379THB8 1-148 MAMQKKHLWYHIRSYLLKEDELPTLISNLNKDLPLIRNLPESHDQYRVFSREYYWSPAYQYFDDPYYGDKGWQNIYTDWQKQGEPIA…
A0A3G6YIN5 1-169 None
A0A808JJT4 238-347 None
A0A378N6F1 513-646 None
A0A0H3K8X2 3-112 None
A0A5C9ENH6 79-223 None
A0A6P3C6C3 49-196 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.