DPCstruct | MC32678

Metacluster Properties and Pfam Annotations

Number of structural domains43
Mean domain length (aa)112 ± 13 aa
Standard deviation of domain lengths12.69
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score77.57
Mean fraction of residues predicted as intrinsically disordered0.73
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)39.85
Pfam Score100.00
Assigned Pfam label(s) PF00010

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H1GAW1 39-145 INKRPTSADKAKSSKMPGSPHSPTNQAKARLTNEQKKKNHIESEKKRRDAIRAGFDRLADVVPGMQGQGRSEAVVLQHTVAYMKGMI…
A0A2G5H843 2-101 NPSETPSSPINSAKSRLTEEQKKRNHIESEKKRREAIRNGFDRLSTIVPGMQGQARSEAIVLAATVDYMRSMINQKDKIYAAAMEKG…
A0A2U3EHH9 1074-1191 None
A0A2D3UWT5 66-173 None
A0A7C8P6D4 178-287 None
A0A370TUQ8 585-700 None
A0A1B7YDF1 47-168 None
A0A1X2I543 281-407 None
D4DGW5 205-326 None
A0A0G4L9A8 564-686 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.