DPCstruct | MC32628

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)436 ± 52 aa
Standard deviation of domain lengths51.91
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score85.56
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)28.13
Pfam Score92.42
Assigned Pfam label(s) PF00347- CL0617- PF01822- PF09366

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H1VF77 10-415 CGGARMPFRAGRIDAVEAGPAGVPEPDTPMDTTRSTFAKAGFSESEMIALVACGHTLGGVHSRNNPHITGLDPTPDTVTKFDSTFDD…
A0A6A6S6Z4 76-516 ISGNVYTGVGGLDGSIQFELASSENNGNAFPGSVAAWAPFLSNRTSLADIVAAAVYTATRSCGGPIVPMRGGRIDATSAGPQGFVPQ…
A0A0G2HW19 4-438 None
A0A4Q2DKT2 2-503 None
W2RZ73 51-545 None
T5ACE9 55-522 None
S3D4X9 77-556 None
A0A0J0XF12 51-523 None
J5SD35 2-351 None
V2X9F3 116-546 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.