DPCstruct | MC32577

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)134 ± 11 aa
Standard deviation of domain lengths11.40
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score84.53
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)29.77
Pfam Score100.00
Assigned Pfam label(s) CL0493

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A846KRU5 1-107 LAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAAHVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHH…
R6ZFD7 3-121 GYQGQVLPAILAAFTLVYLEKFFRKITPQVVSMIVVPFFSLLLSVMAAHFVLGSIGWKVGEAVSTLVFSGITGSFKIVFAAVFGVSY…
A0A380FDV5 9-138 None
A0A4R8A5E4 258-391 None
K9IDE1 175-316 None
A0A0R2AGI4 114-264 None
A0A1X3PAQ4 188-347 None
W7CX65 178-315 None
A0A2N0X9V5 83-222 None
A0A6N6X748 14-151 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.