DPCstruct | MC32554

Metacluster Properties and Pfam Annotations

Number of structural domains35
Mean domain length (aa)144 ± 29 aa
Standard deviation of domain lengths28.62
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score83.54
Mean fraction of residues predicted as intrinsically disordered0.39
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)31.38
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W4JS18 1-112 MRIIPLTLRITSYSAAPPEWPGRPTIHIEGGLAGQSNDLSDARRVHGKVEMVGNGDIRWSLCSEREDGDGEWQSEGVQLGGLGSATG…
A0A137QJ28 65-192 DHRELIEYNKSIDEDTGELDTSLFEDDEFTEVFRRLEVKLKVTRVANDPDHPGRPIIGFVGEMIAPSNSAMYGCVQLMADNHLKWRF…
A0A370TZP2 79-243 None
A0A1J8QEN4 262-404 None
W4KRI3 279-414 None
A0A395T264 338-456 None
G4T680 300-466 None
A0A834RLW0 969-1115 None
A0A438MWS1 802-945 None
A0A0G4M4D8 338-476 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.