DPCstruct | MC3254

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)80 ± 8 aa
Standard deviation of domain lengths8.17
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score87.82
Mean fraction of residues predicted as intrinsically disordered0.46
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)33.29
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4V6Q1M1 8-78 IAEQIGPRVEGVVYYDGPRLVRVESVITDPSESQRILKRRAAQFAVEVIDLHTGDRYPTGAVWTGSDRVIR
G8XFC7 29-106 LTAERARHVHRRRVGPRRPGGVYTSGTDGETYVVLAVHYGADARAALGHPMGWAVTVRTADGRERTHCTPWDPRRDRV
A0A2U3C7G3 3-99 None
A0A1A0IHH0 1-79 None
A0A086H533 3-91 None
A0A6N7L5D9 27-116 None
A0A4Q9HYA7 2-85 None
A0A2N3YU27 58-133 None
A0A1H5PZB2 37-123 None
A0A4S2U3D2 1-79 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.