DPCstruct | MC32536

Metacluster Properties and Pfam Annotations

Number of structural domains533
Mean domain length (aa)301 ± 48 aa
Standard deviation of domain lengths48.22
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score77.90
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)12.61
Pfam Score71.18
Assigned Pfam label(s) PF00057- CL0220- CL0124- CL0293- PF21109

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A540KGD2 16-268 None
A0A1S3MAJ4 231-593 None
A0A498M176 62-331 None
A0A498LKE9 3-300 None
A0A7H9BZ20 280-598 None
A0A2J8WRK1 19-248 None
A0A449BDE9 56-366 None
A0A517RC53 690-1037 None
A0A2C5ZZ47 31-348 None
A0A2C5ZQN8 67-401 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.