DPCstruct | MC32536

Metacluster Properties and Pfam Annotations

Number of structural domains533
Mean domain length (aa)301 ± 48 aa
Standard deviation of domain lengths48.22
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score77.90
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)12.61
Pfam Score71.18
Assigned Pfam label(s) PF00057- CL0220- CL0124- CL0293- PF21109

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6J1VUZ0 8-235 None
A0A3Q3ML74 568-908 None
A0A183CF15 10-366 None
Q2KIK9 162-382 None
A0A2A4N8A1 26-288 None
A0A3M6T7T9 1-296 None
A0A1G7K4F0 114-397 None
A0A287LL15 2-204 None
A0A818MTL5 234-511 None
A0A818MNU2 17-376 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.