DPCstruct | MC32536

Metacluster Properties and Pfam Annotations

Number of structural domains533
Mean domain length (aa)301 ± 48 aa
Standard deviation of domain lengths48.22
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score77.90
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)12.61
Pfam Score71.18
Assigned Pfam label(s) PF00057- CL0220- CL0124- CL0293- PF21109

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I1HN52 46-297 None
Q4W1E5 65-361 None
A0A6G0WE39 27-321 None
A0A7K1LM65 194-434 None
E9H6K7 208-512 None
A0A165FB26 6-400 None
A0A165DGH2 23-351 None
A0A1A7BIT9 389-713 None
A0A2T7P323 37-369 None
A0A2T7P2Q2 17-232 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.