DPCstruct | MC32536

Metacluster Properties and Pfam Annotations

Number of structural domains533
Mean domain length (aa)301 ± 48 aa
Standard deviation of domain lengths48.22
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score77.90
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)12.61
Pfam Score71.18
Assigned Pfam label(s) PF00057- CL0220- CL0124- CL0293- PF21109

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A226ESI0 857-1154 None
A0A226ETM3 736-1051 None
A0A7J6D8E7 149-492 None
A0A226EWU2 60-350 None
A0A2I1E7R2 776-1010 None
A0A7J6CW27 39-240 None
A0A6P8GZS8 105-401 None
A0A2H6KIB9 236-579 None
A0A2H6KIC0 88-417 None
A0A2H6KCW0 646-996 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.