DPCstruct | MC32536

Metacluster Properties and Pfam Annotations

Number of structural domains533
Mean domain length (aa)301 ± 48 aa
Standard deviation of domain lengths48.22
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score77.90
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)12.61
Pfam Score71.18
Assigned Pfam label(s) PF00057- CL0220- CL0124- CL0293- PF21109

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A522BFZ5 223-571 None
A0A4Q4W6C7 12-232 None
A0A5N5TGL9 47-331 None
K7EZZ6 2-311 None
A0A819R2I1 1-202 None
A0A357YJW1 21-251 None
A0A6A5TYZ0 9-402 None
A0A1D2N8I1 658-986 None
A0A2B4STZ7 16-331 None
A0A2B4ST29 6-219 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.