DPCstruct | MC3252

Metacluster Properties and Pfam Annotations

Number of structural domains406
Mean domain length (aa)367 ± 56 aa
Standard deviation of domain lengths56.15
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score84.64
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)15.03
Pfam Score92.61
Assigned Pfam label(s) CL0126- PF20774- CL0220- CL0159- CL0004

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A499VGY2 2-368 IVVLVDFPDKELTATAQHFRDLFFSENTLEHGSVRDYFKEVTHGLVSISGEVVGPVTLPHTLAWYANNNFGIGRPSGEARANIMARD…
F8JWG2 38-418 ALPRTDAWLSEGVTPWDDAHVRPLGTVRAAMVFVRFPDHVPRRAPRQVESAYLPSVPKFYLDASYGKARLAIDPVERWITLPRTAAG…
A0A534ZZC0 168-521 None
A0A074MCT7 19-420 None
A0A2H0YRS5 163-528 None
A0A7K2B226 566-967 None
A0A1I4ATV4 16-401 None
A0A7C4GJB2 24-444 None
A0A6J7VEN8 34-399 None
A0A7X4BY19 73-418 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.