DPCstruct | MC32513

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)189 ± 33 aa
Standard deviation of domain lengths32.78
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score72.90
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)27.22
Pfam Score98.61
Assigned Pfam label(s) PF04654- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Y2FRN8 8-225 LHIAAIAFLVAAWATYAPLLGKFARGTLNTKLSIVRRRWIDLSMRRENRTFDAVMLGHIINSVAFFGSATLIVLAGIVGLFANAGHV…
A0A5J9VHY2 154-364 VLVPLGVMALAVYHLWLLYTILRHPTRTVIGVNGMARKRWVSAMMANTEKNGVLAVQTLRNNIMASTVLATTAITLVSVISVFIGVT…
A0A1D1YYF1 54-259 None
A0A1S8VQ56 65-315 None
A0A068UIA9 13-229 None
A0A6D2HG29 34-218 None
A0A061RLR7 2-154 None
A0A835ETF7 59-239 None
A0A7V2T9E3 17-227 None
A0A822XUI7 2-167 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.