DPCstruct | MC32507

Metacluster Properties and Pfam Annotations

Number of structural domains88
Mean domain length (aa)150 ± 28 aa
Standard deviation of domain lengths27.67
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score76.93
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)31.23
Pfam Score93.17
Assigned Pfam label(s) PF05346- PF10712- PF00643- PF04640

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A836J4X4 8-149 MGNHEMGPPWLIPMLSASYFIPCAVHGESNKSECNMFCLDCMGSAFCSSCLIYHRDHRVVQIRRSSYHNVVRVNEMQKYIDISCVQT…
A0A067EBR2 3-134 SSSSIIPRWLQILLAEKFFSPCVVHECANKNDKNIFCLDCCMSICLHCSHTHRPHHLLQVRRYVYHDVLRLGDAQKLMNCSFVQPYT…
A0A446Q8I2 175-284 None
A0A6J1A441 8-134 None
A0A4Y7L6Y1 8-149 None
A0A194YNC2 13-158 None
A0A0D9VD90 170-318 None
A0A830CJQ5 2-127 None
A0A1Z5RM67 13-131 None
A0A6P5G8D7 1-177 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.