DPCstruct | MC32454

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)212 ± 35 aa
Standard deviation of domain lengths34.91
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score75.53
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)28.60
Pfam Score100.00
Assigned Pfam label(s) PF20173

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A816S3I4 31-236 VRTQVKERLDRSEIVPDAMFVYKCSDACPYMFHFEGCGRPYELSKCPMCKADIGATSYNNPIIRIPPQLQMPIEAGFQFIADYIKTY…
A0A2I1HVK1 1-199 MGTSFYSCICGYRYFIGECGKPVATGSCPDCGKMIGGSDHVPVAGNNRIQIQPLAINHLTGYVGELVSQNMNHFVRSLRPIAYRILH…
A0A2Z6Q3E2 8-186 None
A0A7J5ZWA1 355-511 None
A0A821PUE4 2-244 None
U9UUB4 1-174 None
A0A819XCS6 745-958 None
A0A817FUW3 2-244 None
A0A822G661 189-437 None
A0A822CEW1 1-170 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.