DPCstruct | MC32428

Metacluster Properties and Pfam Annotations

Number of structural domains946
Mean domain length (aa)109 ± 16 aa
Standard deviation of domain lengths15.63
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score81.07
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)15.73
Pfam Score95.53
Assigned Pfam label(s) PF07793- PF07238- PF12945- CL0110- PF00015

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E3BPM8 208-324 None
A0A5C8WRH6 146-246 None
A0A6J6C8N2 516-625 None
V6HMK9 2-90 None
A0A3A4S3Y7 104-215 None
A0A3A4S683 79-171 None
A0A7C3IHQ2 5-101 None
A0A7C4SQQ1 14-133 None
A0A7C4SVM3 2-119 None
A0A148N987 1-120 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.