DPCstruct | MC32428

Metacluster Properties and Pfam Annotations

Number of structural domains946
Mean domain length (aa)109 ± 16 aa
Standard deviation of domain lengths15.63
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score81.07
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)15.73
Pfam Score95.53
Assigned Pfam label(s) PF07793- PF07238- PF12945- CL0110- PF00015

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3B8WRL0 139-258 KAKGMRKFVRMNCQGVRNTEAFFLSGNMMYKMEVLDISSIGMGLKIPLKYCQLFRINTVIPGLNIVLGSKQLKVNAKIFGIKNLGNA…
A0A1G1P7C7 2-106 KERRQYKRIRIDLPAQCKIYGPSEICFSTKVYDISPGGICFLTNDKIELGTQAEIQIKLDNNEKITMKAKVTWSEGPQGAEPARAGV…
A0A1F9CMM4 593-704 None
D4L3W2 598-697 None
A0A7C4LWB3 252-355 None
M1F7T9 1-74 None
A0A7X7XGD0 1-89 None
A0A1Y6B3C2 30-131 None
A0A1Y6BUX0 2-104 None
A0A1E4ZJA7 8-139 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.