DPCstruct | MC32346

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)212 ± 40 aa
Standard deviation of domain lengths40.11
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score81.02
Mean fraction of residues predicted as intrinsically disordered0.44
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)33.53
Pfam Score84.93
Assigned Pfam label(s) CL0023- PF08155- CL0669

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2J6L4F1 16-237 KTALLVATRSTMVNQPNNLQSLEGISEDDMKLVEEMKLEAMKISVVEGQQVLLTMSTLTKEGVTVFHVAMPKPCDQKERHVCIPESI…
L5K785 8-208 FPVVETSTLTEEGVIKVKTEACDRLLAHRVETKMKGNKVNEVLNRLHLAVPNKRDDKERPPFIPEGVVARRKRMETGEPRRKRERDI…
A0A197JRP3 152-316 None
A0A4U0WWH5 286-495 None
F0VGG3 273-530 None
A0A7R9HI60 47-248 None
M3US28 1-174 None
A0A7J8VR90 2-189 None
A0A183HG39 92-290 None
A0A183WA06 19-252 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.